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Impact of Persistent Cytomegalovirus Infection on Dynamic Changes in Human Immune System Profile

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By Rosanna Vescovini, Anna Rita Telera, Mario Pedrazzoni, Barbara Abbate, Pietro Rossetti
| PLOS
Human cytomegalovirus (HCMV) imprints the immune system after primary infection, however its effect during chronic infection still needs to be deciphered. In this study we report the variation of blood cell count along with anti-HCMV IgG and T cell responses to pp-65 and IE-1 antigens, that occurred after an interval of five years in a cohort of 25 seropositive healthy adults.
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