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FLOT vs CROSS Among Patients With Pathological Complete Response in Esophageal Adenocarcinoma
Key Points Question Does survival after pathological complete response differ between 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) and the Chemoradiotherapy for Oesophageal Cancer Followed by Surgery Study protocol (CROSS)? Findings In this cohort study of 297 patients with pathological complete response after neoadjuvant therapy, perioperative FLOT was associated with significantly better overall and disease-free survival compared with CROSS.
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