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Barbara Altendorfer on Muck Rack

Barbara Altendorfer

As seen in: MDPI, The Journal of Immunology
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Articles

Montelukast alleviates neuroinflammation and improves motor functions in the line 61 model of Parkinson's disease: An exploratory study

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By Marco Zattoni, Michael Unger, Barbara Altendorfer, Katharina Strempfl
| neurotherapeuticsjournal.org
Keywords Leukotrienes Repurposing Parkinson Alpha-synuclein Neuroinflammation Introduction Parkinson's disease (PD) is the second most common neurodegenerative disorder, affecting over six million people worldwide [1]. Its pathological characteristics comprise the accumulation of misfolded α-synuclein protein (α-syn) in various brain regions and the progressive loss of dopaminergic neurons in the substantia nigra (SN), leading to reduced striatal dopamine levels [2]⁠.
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Omega-3 EPA Supplementation Shapes the Gut Microbiota Composition and Reduces Major Histocompatibility Complex Class II in Aged Wild-Type and APP/PS1 Alzheimer’s Mice: A Pilot Experimental Study

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By Barbara Altendorfer, Ariane Benedetti, Heike Mrowetz, Sabine Bernegger
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Transcriptomic Profiling Identifies CD8+ T Cells in the Brain of Aged and Alzheimer’s Disease Transgenic Mice as Tissue-Resident Memory T Cells

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By Barbara Altendorfer, Michael Stefan Unger, Rodolphe Poupardin, Anna Hoog
| The Journal of Immunology Verified
Flow cytometry and IHC analysis confirmed the presence of Trm CD8+ T cells in the brain of aged WT and APP-PS1 animals To further investigate the tissue-resident profile of brain CD8+ T cells and validate our mRNA-seq data, we used IHC and flow cytometry for detailed analysis of brain and blood CD8+ T cells of WT and APP-PS1 mice (24–25 mo old) (Figs 3, 4).
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