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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Lateral Hypothalamic Glutamate and GABA Neurons Cooperatively Shape Striatum-Wide Dopamine Dynamics During Consumption
Abstract The lateral hypothalamic area (LHA) contains GABAergic and glutamatergic neurons that converge on the midbrain dopamine system and exert opposing influences on consummatory feeding behavior. However, the activity dynamics of these populations during consumption and their impact on striatal dopamine release remain poorly understood.
Rapid fluctuations in histamine associated with intake of nutritive and non-nutritive solutions
Abstract The neurotransmitter histamine is involved in control of food intake, yet its dynamics during individual feeding episodes remain unexplored. Therefore, we used the novel genetically-encoded histamine sensor, HisLightG, combined with fiber photometry to measure histamine release in two hypothalamic regions critical in the food-suppressive effects of histamine, the paraventricular nucleus of the hypothalamus (PVH), and the ventromedial hypothalamus (VMH).
An inhibitory circuit from central amygdala to zona incerta drives pain-related behaviors in mice
Abstract Central amygdala neurons expressing protein kinase C-delta (CeA-PKCδ) are sensitized following nerve injury and promote pain-related responses in mice. The neural circuits underlying modulation of pain-related behaviors by CeA-PKCδ neurons, however, remain unknown. In this study, we identified a neural circuit that originates in CeA-PKCδ neurons and terminates in the ventral region of the zona incerta (ZI), a subthalamic structure previously linked to pain processing.
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