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Effects of early life adversity on socially learned analgesia and empathy in virtual reality
Abstract Many digital interventions rely on learning from social and contextual cues, yet it remains unclear how early life adversity influences responsiveness to these mechanisms. Early life adversity (ELA), commonly assessed using Adverse Childhood Experiences (ACEs), is associated with long-lasting alterations in stress regulation and social information processing that may shape learning-based pain modulation.
A critical role of affective content in the analgesic effect of virtual reality: a cross-sectional within-subject study
Keywords Cognitive engagement Attention Emotional regulation Distraction Skin conductance Ambient sound Evidence before this study Prior to conducting this study, we performed a systematic search of the literature to identify relevant evidence on virtual reality (VR)–based analgesia and pain modulation. We searched PubMed, Web of Science, and PsycINFO from inception through June 2025.
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