Barbara C. Gärtner
Munich
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STIKO-Empfehlung: MF59-adjuvantierter Influenza-Impfstoff für Menschen ≥ 60 Jahre
Die Ständige Impfkommission (STIKO) hat im Oktober 2024 ihre Empfehlung zur saisonalen Influenza-Impfung für Personen ab 60 Jahren angepasst. Aufgrund neuer Studiendaten wird der MF59-adjuvantierte Influenza-Impfstoff nun neben dem Hochdosis-Impfstoff gleichwertig empfohlen: Es zeigte sich eine Überlegenheit des MF59-adjuvantierten Impfstoffs hinsichtlich der Effektivität im Vergleich zu nicht-adjuvantierten Standardimpfstoffen bei älteren Erwachsenen.
SARS-CoV-2-specific cellular and humoral immunity after bivalent BA.4/5 COVID-19-vaccination in previously infected and non-infected individuals - Nature Communications
Abstract Knowledge is limited as to how prior SARS-CoV-2 infection influences cellular and humoral immunity after booster-vaccination with bivalent BA.4/5-adapted mRNA-vaccines, and whether vaccine-induced immunity may indicate subsequent infection. In this observational study, individuals with prior infection (n = 64) showed higher vaccine-induced anti-spike IgG-antibodies and neutralizing titers, but the relative increase was significantly higher in non-infected individuals (n = 63).
Dental aerosol-producing treatments: Comparison of contamination patterns of face shields and surgical masks
Abstract During the COVID-19 pandemic, dental face shields were recommended to protect the eyes. This study aimed to examine to what extent face shield and mask contamination differ when a pre-procedural mouth rinsing with Chlorhexidine (CHX) is conducted before treatment. In this prospective, randomized study, three groups of subjects were formed (rinsing with 0.1% CHX, water, or no rinsing (control) before aerosol-producing treatments).
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