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Barbara Corneo on Muck Rack

Barbara Corneo

As seen in: Nature, Stem Cell Reports
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Articles

Temporal multiomics gene expression data across human embryonic stem cell-derived polyhormonal cell differentiation - Scientific Data

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By Abdurrahman Keskin, Barbara Corneo
| Nature Verified
Abstract Human embryonic stem cells (hESCs) provide a powerful in vitro model to study lineage specification and the regulatory programs underlying early human development. Here, we present a high-resolution, temporal multi-omics dataset tracking mRNA, translation, and protein expression dynamics during hESC differentiation into definitive endoderm and subsequent polyhormonal (PH) cells, a key pancreatic lineage.
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Derivation and analysis of human somatic sensory neuron subtypes facilitated through fluorescent hPSC reporters

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By Eti Malka-Gibor, Katherine Oliver, Shirley Chen, Alejandro Garcia-Diaz, Damian Williams, Jordan Henry, Busra Turan Akcan, Barbara Corneo
| Stem Cell Reports Verified
Keywords peripheral neuropathy hESC-derived sensory subtypes nociceptors touch receptors proprioceptors hESC fluorescent reporters for sensory subtypes Crispr/Cas9 gene editing Introduction Peripheral sensory neuropathy (PSN) is a neurological condition caused by heritable or idiopathic metabolic disease, exposure to toxic substances (including chemotherapeutic agents), or physical nerve damage (Gomatos and Rehman 2022).
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Temporal multiomics gene expression data of human embryonic stem cell-derived cardiomyocyte differentiation - Scientific Data

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By Abdurrahman Keskin, Barbara Corneo
| Nature Verified
Abstract Human embryonic stem cells (hESCs) serve as a valuable in vitro model for studying early human developmental processes due to their ability to differentiate into all three germ layers. Here, we present a comprehensive multi-omics dataset generated by differentiating hESCs into cardiomyocytes via the mesodermal lineage, collecting samples at 10 distinct time points.
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