Barbara D. Fontana

ANOVA analysis of variance ASD autism spectrum disorder CAS conspecific alarm substance CPP conditioned place preference CTRL control group FMP Y-maze free movement pattern Y-maze NTT novel tank diving test RM-ANOVA repeated measures analysis of variance SEM standard error of the mean 1 Introduction Individual differences are essential for species survival, influencing adaptability to changing environments and shaping responses to threats (Sansom et al. 2009; Shaw 2020).

Abstract The reproducibility crisis in bioscience, characterized by inconsistent study results, impedes our understanding of biological processes. Global collaborative studies offer a unique solution to this problem. Here, we present a global collaboration using the zebrafish (Danio rerio) novel tank test, a popular behavioral assay for anxiety-like responses. We analyzed data from 20 laboratories worldwide, focusing on housing conditions and experimental setups.

Abstract Environmental factors play a role in the development and severity of neuropsychiatric disorders. Externalizing disorders (EDs) are linked to genetic and environmental factors and frequently co-occur with internalizing disorders (ID), such as anxiety. Individuals experiencing both ED/ID are often among the most likely to seek healthcare services, as this co-occurrence is associated with more severe symptomatology and greater functional impairment.