Barbara Garmy-Susini
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Study of the lymphatic system in the wall of abdominal aortic aneurysms: Regulation and pathological involvement
Abdominal aortic aneurysm (AAA) is a chronic inflammatory condition characterized by progressive degradation of the aortic wall. Lymphangiogenesis, eosinophils (EOS) and pro-resolving lipid mediators derived from 15-lipoxygenase (15LO) emerge as important players in immune regulation. However, the coordinated role of these elements in AAAs remains unclear. Recent literature presented intra-aortic eosinophils as a protective agent for aneurysmal development.
lncRNA LINC-PINT controls lymphatic function and inflammatory profile in lymphedema
Abstract Lymphedema is a lymphatic dysfunction leading to an accumulation of fluid and fat in the arm or leg. Here, we performed noncoding RNA profiling of human breast cancer–induced secondary lymphedema. We identified the long intergenic non–protein coding RNA, P53-induced transcript (LINC-PINT), as essential for the lymphedema development. LINC-PINT is the most expressed lncRNA in human lymphatic endothelial cells (LECs) under stress condition.
Property Value Status Version Ad File Disable Ads Flag Environment Moat Init Moat Ready Contextual Ready Contextual URL Contextual Initial Segments Contextual Used Segments AdUnit SubAdUnit Custom Targeting Ad Events Invalid Ad Sizes Full length articleArticles in PressOpen access aDepartment of Vascular Surgery, University Hospital of Rangueil, Toulouse, France bUniversity of Poitiers, School of Medicine, Poitiers, France cUniversité de Toulouse, Inserm UMR 1297, UT3, Toulouse, France...
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