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Retrospective HRMS Screening and Dedicated Target Analysis Reveal a Wide Exposure to Pyrrolizidine Alkaloids in Small Streams
Introduction The occurrence of bioactive anthropogenic compounds in surface waters has increasingly been investigated in the last years because of their critical impact on human and environmental health.(1−3) In contrast, phytotoxins have, with few exceptions, not been considered, although they are produced by a wide range of plant species, and many of them are sufficiently persistent and mobile to reach the aquatic environment.(4,5) Among them, pyrrolizidine alkaloids (PAs) were recently...
Chloromethyl-triazole: A new motif for site-selective pseudo-acylation of proteins
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