Barbara Heude
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Epigenetic gestational age acceleration and indicators of BMI trajectories in childhood
Abstract Positive epigenetic gestational age acceleration, an epigenetic gestational age higher than the clinical gestational age, has been associated with higher birthweight and lower weight from 5 years onwards. We investigated the associations of epigenetic gestational age acceleration with age and BMI at adiposity peak and rebound to better understand epigenetic mechanisms associated with childhood BMI trajectories.
Pre-pregnancy body mass index and biomarkers of inflammation at birth
Abstract High pre-pregnancy body mass index (BMI), accompanied by chronic low-grade inflammation may predispose offspring to adverse health outcomes by interfering with fetal development. However, the association between maternal pre-pregnancy obesity and elevated inflammatory biomarkers in the mother or fetus remains controversial. This study analyzed the association between pre-pregnancy BMI and biomarkers of inflammation in maternal serum and cord blood at birth in two large birth cohorts.
Longitudinal associations between screen time and whole-body adiposity during the first decade of life: insights from the GUSTO cohort
Abstract Childhood obesity remains a pressing public health challenge worldwide. With screen viewing emerging as a major contributor to sedentary time, it is crucial to assess the extent to which screen viewing contributes to excessive body fat in children. The aim of this study was to examine the associations between screen time and subsequent adiposity in children from the Singapore GUSTO cohort.
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