Barbara Hollunder

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-48731-1, published online 31 May 2024 The original version of this Article contained an error in Figure 2, in which the statistical analyses in the insets of panel B were incorrectly reported. Permutation tests were inadvertently reported instead of circular tests and cross-validation values.

Abstract Deep Brain Stimulation can improve tremor, bradykinesia, rigidity, and axial symptoms in patients with Parkinson’s disease. Potentially, improving each symptom may require stimulation of different white matter tracts. Here, we study a large cohort of patients (N = 237 from five centers) to identify tracts associated with improvements in each of the four symptom domains. Tremor improvements were associated with stimulation of tracts connected to primary motor cortex and cerebellum.

R.L. reports personal fees from Medtronic. M.D.F. has intellectual property on the use of brain connectivity imaging to analyze lesions and guide brain stimulation, is a consultant for Magnus Medical, Soterix, Abbott, and Boston Scientific, and has received research funding from Neuronetics. A.H. reports lecture fees for Boston Scientific and is a consultant for FxNeuromodulation and Abbott.