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Barbara Illi on Muck Rack

Barbara Illi

As seen in: Nature, MDPI
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Articles

α-ketoglutarate/succinate ratio imbalance impairs thymine DNA glycosylase function and base excision repair process increasing susceptibility to pancreatic cancer | Cell Death & Disease

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By Silvia Malatesta, Virginia Vigiano Benedetti, Emanuela Salviati, Barbara Illi, Isabella Manni, Emanuele Middonti, Valerio Licursi, Francesca Troilo, Gianni Colotti, Lina Cipolla, Simone Sabbioneda, Livia Perfetto, Giulia Piaggio, Federico Bussolino, Federica Di Nicolantonio, Pietro Campiglia, Eduardo Sommella, Mattia Mori, Chiara Cencioni, Francesco Spallotta
| Nature Verified
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, with chronic metabolic disorders increasing risk and severity. Prolonged exposure to altered metabolism changes specific metabolite levels, impacting epigenetic landscape contributing neoplastic lesion acquisition.
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The Role of HDAC6 in Glioblastoma Multiforme: A New Avenue to Therapeutic Interventions?

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By Francesco Spallotta, Barbara Illi
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Myc beyond Cancer: Regulation of Mammalian Tissue Regeneration

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By Barbara Illi, Sergio Nasi
| MDPI
Abstract : Myc is one of the most well-known oncogenes driving tumorigenesis in a wide variety of tissues. From the brain to blood, its deregulation derails physiological pathways that grant the correct functioning of the cell. Its action is carried out at the gene expression level, where Myc governs basically every aspect of transcription.
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