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Barbara K. Mathiesen on Muck Rack

Barbara K. Mathiesen

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Articles

PET imaging of TREM1 identifies CNS-infiltrating myeloid cells in a mouse model of multiple sclerosis

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By Aisling Chaney, Cristina Mastini, Barbara K. Mathiesen, Haley C. Cropper
| Science Magazine Verified
Abstract Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) that causes substantial morbidity and diminished quality of life. Evidence highlights the central role of myeloid lineage cells in the initiation and progression of MS. However, existing imaging strategies for detecting myeloid cells in the CNS cannot distinguish between beneficial and harmful immune responses.
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Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma

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By Aisling Chaney, Cristina Mastini, Barbara K. Mathiesen, Marco Campisi
| Science Magazine Verified
(0)eLetters eLetters is a forum for ongoing peer review. eLetters are not edited, proofread, or indexed, but they are screened. eLetters should provide substantive and scholarly commentary on the article. Embedded figures cannot be submitted, and we discourage the use of figures within eLetters in general. If a figure is essential, please include a link to the figure within the text of the eLetter. Please read our Terms of Service before submitting an eLetter. Log In to Submit a Response
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Long-acting refillable nanofluidic implant confers protection against SHIV infection in nonhuman primates

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By Aisling Chaney, Cristina Mastini, Barbara K. Mathiesen, Fernanda P. Pons-Faudoa
| Science Magazine Verified
Abstract The impact of pre-exposure prophylaxis (PrEP) on slowing the global HIV epidemic hinges on effective drugs and delivery platforms. Oral drug regimens are the pillar of HIV PrEP, but variable adherence has spurred development of long-acting delivery systems with the aim of increasing PrEP access, uptake, and persistence.
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