Barbara Kirchner
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Carboxylic Acid Co-Catalysts Facilitate N-Heterocyclic Carbene Organocatalysis Through Proton Relay and Polarization Effects
1 Introduction Due to their versatility and selectivity, organocatalytic processes offer valuable alternatives to transition metal catalysis for synthetic strategies, while avoiding the use of toxic and costly heavy metals [1-5]. One of the most prominent families of organocatalysts is azolium salts, the reactions of which are generally explained through their ability to produce N-heterocyclic carbenes (NHCs).
Denaturation of Water in Alkaline Melts
1 Introduction To increase the sustainability of chemical industries, alternative reaction pathways are being sought that require less energy, are more atomically efficient, and produce less waste overall. New approaches include chemical reactions using the hydroflux method. A hydroflux medium can be considered a highly concentrated aqueous electrolyte solution or the melt of a wet salt.
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