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Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice
Do mother’s antibodies know best? Infants are susceptible to many infections. One promising strategy to shield them is through vaccination of mothers during pregnancy, thus providing maternal antibodies that can temporarily protect infants from disease. However, maternal antibodies can also prevent infants from developing their own antibody responses that are necessary for long-term protection. Willis et al.
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