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Barbara Ladisich on Muck Rack

Barbara Ladisich

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Characterization, immune cell phenotyping and differential gene expression analysis of brain metastases and primary breast cancer samples

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By Franz Josef Gassner, Gabriel Rinnerthaler, Alejandra Gonzalez-Martinez, Stephan Drothler, Richard Greil, Roland Geisberger, Christoph Schwartz, Karl Sotlar, Beate Alinger-Scharinger, Markus Steiner, Nadja Zaborsky, Simon Peter Gampenrieder, Vanessa Castagnaviz, Thomas Parigger, Theo F. J. Kraus, Alexander Romagna, Barbara Ladisich, Cornelia Hauser-Kronberger
| Nature Verified
Abstract Tumor heterogeneity in breast cancer is well recognized, but research has largely focused on primary tumors, while metastatic lesions, particularly brain metastases (BM), remain understudied. With the rising incidence of BM in metastatic breast cancer (MBC) and their poor prognosis, a deeper understanding of the molecular mechanisms driving BM formation, progression, and immune evasion is crucial for developing better therapeutic strategies.
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