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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
H-1 Parvovirus-Induced Oncolysis and Tumor Microenvironment Immune Modulation in a Novel Heterotypic Spheroid Model of Cutaneous T-Cell Lymphoma
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Phase 2 trial of oncolytic H-1 parvovirus therapy shows safety and immune cell activity in patients with metastatic pancreatic ductal adenocarcinoma
Research Article Jacek Hajda, Barbara Leuchs, Assia L. Angelova, Veronika Frehtman, Jean Rommelaere, Mieke Mertens, Maximilian Pilz, Meinhard Kieser, Ottheinz Krebs, Bernard Huber, Christine E. Engeland, Athanasios Mavratzas, Nicolas Hohmann, Jutta Schreiber, Dirk Jäger, Niels Halama, Oliver Sedlaczek, Matthias M.
SUMOylation Targets Adeno-associated Virus Capsids but Mainly Restricts Transduction by Cellular Mechanisms
Virus-Cell Interactions Qingxin Chen, Robin Njenga, Barbara Leuchs, Susanna Chiocca, Jürgen Kleinschmidt, Martin Müller Colin R. Parrish, Editor DOI: 10.1128/JVI.00871-20 ABSTRACT Adeno-associated virus (AAV) has proven to be a promising candidate for gene therapy due to its nonpathogenic nature, ease of production, and broad tissue tropism. However, its transduction capabilities are not optimal due to the interaction with various host factors within the cell.
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