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Barbara Meier-Schiesser on Muck Rack

Barbara Meier-Schiesser

As seen in: Nature
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Articles

LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes | Cell Death & Disease

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By Jennifer Keller, Judit Danis, Takashi Satoh, Barbara Meier-Schiesser, Lajos V. Kemeny, Steve Pascolo, Lars E. French, Thomas M. Kündig, Isabella Krehl, Márta Széll, W. Wei-Lynn Wong
| Nature Verified
Abstract The Interleukin-36 (IL-36) cytokine family have emerged as important players in mounting an inflammatory response at epithelial barriers and tailoring appropriate adaptive immune responses. As members of the Interleukin-1 superfamily, IL-36 cytokines lack a signal peptide for conventional secretion and require extracellular proteolysis to generate bioactive cytokines.
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Culprit Drugs Induce Specific IL-36 Overexpression in Acute Generalized Exanthematous Pustulosis

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By Laurence Feldmeyer, Dragana Jankovic, Barbara Meier-Schiesser, Mark Mellett
| jidonline.org
Introduction Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction (ADR) caused mainly by antibiotics, antimalarials, and antifungals (Sidoroff et al., 2001xSidoroff et al., 2001Sidoroff, A., Halevy, S., Bavinck, J.N., Vaillant, L., and Roujeau, J.C. Acute generalized exanthematous pustulosis (AGEP)—a clinical reaction pattern. J Cutan Pathol. 2001; 28: 113–119 Google ScholarSee all ReferencesSidoroff et al., 2001).
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