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Long-Term Treatment with Fluoroethylnormemantine (FENM) Alleviated Memory Deficits, Amyloid Pathology, and Microglial Reaction in APP/PS1 Mice
About 50 million people worldwide suffer from dementia, among whom two-thirds have Alzheimer’s disease (AD). (1) AD symptoms are a chronic decline in short-term memory and cognition that impairs daily behavior and ultimately leads to dementia and death. It is characterized by amyloid plaques, neurofibrillary tau tangles, and aggregates of misfolded proteins, throughout the brain.
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