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Barbara Monti on Muck Rack

Barbara Monti

As seen in: Nature, Wiley Online Library, Frontiers, Royal Society of Chemistry, LexBlog, Concurrences
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Articles

Combined ketone body and glutamine supplementation restores aerobic energy production in AGC1-deficient neuronal progenitors - Cell Death & Disease

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By Felix Distelmaier, Michele Protti, Giacomo Volpe, Massimo Bonora, Anna M. Campana, Giuseppe Fiermonte, Paolo Pinton, Douglas C. Wallace, Barbara Monti, Veronica Addabbo
| Nature Verified
Abstract AGC1 deficiency is a rare, early-onset encephalopathy caused by mutations in the SLC25A12 gene, encoding the mitochondrial aspartate/glutamate carrier isoform 1 (AGC1). Patients exhibit epileptic encephalopathy, cerebral hypomyelination, severe hypotonia, and global developmental delay. A hallmark biochemical feature of AGC1 deficiency is reduced brain N-acetylaspartate (NAA), a key metabolite involved in myelin lipid synthesis.
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Targeting Lewy body dementia with neflamapimod‐rasagiline hybrids

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By Barbara Monti, Claudia Albertini, Sabrina Petralla, Francesca Massenzio
| Wiley Online Library Verified
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. Supporting Information Filename Description ardp202300525-sup-0001-Albertini-ArchPharm_SupplMat_InChI.doc68.5 KB Supporting information. ardp202300525-sup-0002-Albertini-SupportingInformation.docx3.1 MB Supporting information. REFERENCES 1 World Alzheimer Reports. 2023. 2, , , Neurotherapeutics 2022, 19, 55. 3, , , , , , , , , J. Neurol. Neurosurg. Psychiatry 2018, 89, 339. 4, , , , , , , , , , , , , Brain 2018, 141, 3415.
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Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth

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By Miguel Sá Fernandes, Barbara Monti, Jose G Fernandez-Bolanos, Eleonora Poeta
| Royal Society of Chemistry Verified
Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth We have applied the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction to prepare a library of ten coumarin-azasugar-benzyl conjugates and two phthalimide-azasugar-benzyl conjugates with potential anti-Alzheimer and anti-cancer properties.
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