Barbara O. Rothbaum
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Post-traumatic stress disorder - Nature Reviews Disease Primers
Abstract Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder that develops after exposure to a severe traumatic event. PTSD is characterized by intrusive re-experiencing of traumatic memories, avoidance of trauma reminders, negative alterations in cognition and mood, and changes in arousal and reactivity. PTSD is prevalent, with tens of millions of patients in the USA alone affected.
State of the Science: MDMA-assisted psychotherapy for the treatment of posttraumatic stress disorder
L. A., Rothbaum, B. O., Sippel, L. M., Maples-Keller, J., & Schnurr, P. P. (2026). State of the Science: MDMA-assisted psychotherapy for the treatment of posttraumatic stress disorder. Journal of Traumatic Stress, 1–15. Morland, https://doi.org/10.1002/jts.70060 REFERENCES , , & (2025). Self-compassion mediates treatment effects in MDMA-assisted therapy for posttraumatic stress disorder. European Journal of Psychotraumatology, 16(1), Article 2485513.
Harnessing psychedelics for treating posttraumatic stress disorder: Does the science support all the hype?
As demand grows for improvements in the ability to treat posttraumatic stress disorder (PTSD), increasing attention is being devoted to the potential contribution of psychedelics and related drugs. Although the area has generated considerable interest over recent years, it has also been the subject of controversy and has raised complex issues for clinicians, researchers, and funding bodies, as well as for individuals living with PTSD.
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