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Barbara Peracino on Muck Rack

Barbara Peracino

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Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells

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By Laura Di Blasio, Livio Trusolino, Alberto Puliafito Verified, Andrea Bertotti, Valentina Monica, Luca Primo, Marianela Vara-Messler, Barbara Peracino, Elena Masti, Vanesa Cepas-López
| Nature Verified
Abstract Several epidemiological and preclinical studies suggest that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) exert anticancer activity at multiple stages of colorectal cancer (CRC) progression. However, inconsistent clinical evidence and the lack of a clearly defined molecular mechanism underlying the antitumor effects of n-3 PUFAs have raised doubts about their efficacy as anticancer therapies.
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