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Miglustat in Alzheimer's Disease Associated With Heterozygous NPC1 Mutation: Exploratory Case Series and Preliminary Findings
1 Introduction The estimated number of people worldwide affected by dementia was more than 55 million in 2019; for 2050 some sources predict more than 150 million cases globally [1]. Alzheimer's disease (AD) is the leading cause of dementia, accounting for 60% to 80% of cases and afflicting about 24 million people worldwide [2].
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