Skip To Main Content
Barbara Rothen on Muck Rack

Barbara Rothen

As seen in: Chemistry World
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Barbara

Contact Barbara, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Organometallic Cobalamin Anticancer Derivatives for Targeted Prodrug Delivery via Transcobalamin-Mediated Uptake

|
By Emmanuel Kottelat, Jeremie Rossier, Barbara Rothen
| Chemistry World Verified
Herein we report the synthesis of new water-soluble vitamin B12 prodrugs bearing metal complexes at the ?-upper side of the cobalt center. A total of three derivatives with the general design {Co-C?C-bpy-M}, where M represents a cytotoxic metal complex, were prepared and tested for their cytotoxicity against MCF-7 breast cancer cells. The metal choice was oriented on the eminent Pt and promising Ru and Re species to demonstrate the general applicability of the approach.
Open in Who Shared Issue with article?
See all 1 articles