Barbara Seliger
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Fibroblast activation protein (FAP)-mediated promotion of metastasis via the FN1-TGFβ axis and immune suppression in aggressive thyroid cancer - Journal of Translational Medicine
TC cell lines of distinct subtypes were kindly provided by Prof. Dr. Cuong Hoàng-Vu (Laboratory Surgical Research, University Hospital Halle, Halle, Germany, and Prof. Dr. Stefan Huettelmaier, Medical Faculty of the Martin Luther University Halle-Wittenberg, Institute for Molecular Medicine, Section Molecular Cell Biology, Halle, Germany).
HIV status alters immune cell infiltration and activation profile in women with breast cancer - Nature Communications
Abstract The breast cancer (BC)-related mortality is higher and the immunity is altered in women living with HIV (WLWH) compared to HIV-negative women. Therefore, tumor samples of 296 black BC patients from South Africa and Namibia with known age, HIV status, tumor stage, hormone receptor and HER2 status and overall survival (OS) are analyzed for components of the tumor microenvironment (TME).
Immune modulatory microRNAs in tumors, their clinical relevance in diagnosis and therapy
Clinical relevance of immune modulatory miRNAs Based on the differential expression pattern in tumors, the use of im-miRNAs as diagnostic and/or prognostic tools for various cancer types to predict patients’ outcome has been investigated.107 In addition, the clinical relevance of im-miRNAs was demonstrated based on the targeted pathway and their relevance in the respective cancer type.
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