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Barbara Sinigaglia on Muck Rack

Barbara Sinigaglia

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Articles

Azacitidine maintenance after allogeneic hematopoietic stem cell transplantation in high-risk AML: a single-center retrospective study

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By Francesco De Felice, Margherita Ursi, Francesco Barbato, Marcello Roberto, Gabriele A. Fontana, Luca Zazzeroni, Salvatore Nicola Bertuccio, María Elena Naddeo, Irene Salamon, Serena De Matteis, Francesca Ricci, Gianluca Storci, Enrico Maffini, Francesca Bonifazi, Federica Ardizzoia, Francesco Iannotta, Michele Loffredo, Sadia Falcioni, Enrica Tomassini, Barbara Sinigaglia, Elisa Dan, Elena Campanini, Daria Messelodi, Massimiliano Bonafè
| Nature Verified
In patients with acute myeloid leukemia (AML) undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), disease relapse remains the leading cause of transplant failure [1]. Growing evidence indicates that immune escape represents a major mechanism driving post-transplant relapse [2]. Hypomethylating agents have gained interest due to their dual properties, antileukemic and immunomodulatory [3].
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