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Depression and Anxiety in Association with Polypharmacy in Patients with Multiple Sclerosis
1. Introduction Multiple sclerosis (MS) is an immune-mediated disease that affects the central nervous system [1]. Worldwide, more than 2.8 million people suffer from MS, representing the most common non-traumatic neuroimmunological disease in young adults [2,3]. MS symptoms can vary from acute unilateral optic neuritis, diplopia, nystagmus, trigeminal neuralgia, sensory loss, motor disturbances, cerebellar ataxia, urinary urge incontinence and constipation to erectile dysfunction [4,5,6,7].
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