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Barbara Tremmel on Muck Rack

Barbara Tremmel

As seen in: Nature
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Articles

Creating bottom-up RNA transfer vehicles from synthetic protein assemblies

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By Christoph Gruber, Christopher Lang, Brice Beinsteiner, Karoline Kadletz, Zhe Ma, Leon Hetzel, Juliane Merl-Pham, Tatjana Dorn, Karin Ganea, Niklas Armbrust, Julian Geilenkeuser, Gil Westmeyer, Elvir Becirovic, Martin Biel, Rouzanna Istvanffy, Dong-Jiunn Jeffery Truong, Fabian J. Theis, Gregor Ebert, Alessandra Moretti, Ali Erturk, Andrea Bähr, Christian Kupatt, Marion Jasnin, Nikolai Klymiuk, Florian Giesert, Wolfgang Wurst, Maren Kirstin Schuhmacher, Ricardo M. W. Ruijpers, Lyupka Mazneykova, Ariane Krus, Barbara Tremmel, Friederike Reinhardt, Lucie Casalta, Dina Y. Otify, Iolo Balken, Marina Luchner, Lea Bauersachs, Natascha Wieser, Alexander Emrich, Emirhan Yağmur, Katrin Rager, Gauhar Sagindykova, Daniela M. Vogt Weisenhorn
| Nature Verified
Abstract Evolution guides biological systems to populate ecological niches, with viruses among the most successful examples of this principle. Viruses evolved over billions of years to efficiently transfer genetic information. Although viruses are highly diverse, most have converged towards remarkable similarity in the size and shape of their capsids1,2. By contrast, generative models for protein design enable the creation of protein architectures that are absent from nature3,4,5.
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