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Barbora Burýšková on Muck Rack

Barbora Burýšková

As seen in: Nature, BioRxiv
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Articles

Building a syntrophic Pseudomonas putida consortium with reciprocal substrate processing of lignocellulosic disaccharides

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By Barbora Burýšková, Jesus Miro-Bueno, Barbora Popelarova, Barbora Gavendova
| BioRxiv
Abstract Synthetic microbial consortia can leverage their expanded enzymatic reach to tackle biotechnological challenges too complex for single strains, such as lignocellulose valorisation. The benefit of metabolic cooperation comes with a catch - installing stable interactions between consortium members. We constructed a syntrophic consortium of Pseudomonas putida strains for lignocellulosic disaccharide processing.
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Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose - Nature Communications

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By Pavel Dvořák, Barbora Burýšková, Barbora Popelarova, Birgitta E Ebert, Heiko Hayen, Victor de Lorenzo, Lars M. Blank, Tibor Botka, Dalimil Bujdoš, Alberto Sánchez-Pascuala, Hannah Schöttler
| Nature Verified
Abstract To broaden the substrate scope of microbial cell factories towards renewable substrates, rational genetic interventions are often combined with adaptive laboratory evolution (ALE). However, comprehensive studies enabling a holistic understanding of adaptation processes primed by rational metabolic engineering remain scarce.
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Genomic and metabolic plasticity drive alternative scenarios for adapting Pseudomonas putida to non-native substrate D-xylose.

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By Pavel Dvořák, Barbora Burýšková, Barbora Popelarova, Birgitta E Ebert
| BioRxiv
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