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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Perivascular RELM⍺-positive synovial macrophages recruit monocytes at the onset of inflammatory arthritis
Abstract Macrophages, monocytes and neutrophils are major types of myeloid cells involved in inflammatory diseases, such as rheumatoid arthritis (RA). Recent scRNA-seq studies identified a remarkable diversity of synovial macrophages but, with the exception of lining macrophages, their geographical location and specific roles remain largely unexplored.
Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation
Our study highlights lining macrophages as critical upstream instigators of joint inflammation.
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