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Homologous recombination mutants cause differing lethality between h − and h + Schizosaccharomyces pombe strains due to mat1 heterochromatin
ChIP chromatin immunoprecipitation DSB double-strand break H3K9me histone H3 lysine 9 methylation HR homologous recombination MTS mating-type switching qPCR quantitative polymerase chain reaction Introduction The fission yeast Schizosaccharomyces pombe spends most of its life cycle in the haploid state and exists as one of two mating types, minus (M) or plus (P). Mating occurs only between cells of opposite types. Depending on the stability of mating type inheritance, S.
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