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Barbra Johnson Sasu on Muck Rack

Barbra Johnson Sasu

As seen in: Nature
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Articles

The therapeutic gene editing solution - cell therapy for solid tumors

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By Barbra Johnson Sasu, Pallavur Sivakumar, Bristol Myers Squibb, James Trager
| insights.bio
Engineered immune cell therapy has revolutionised the field of cancer therapeutics. However, the success observed against haematological malignancies has not translated well to the more complex and refractory solid tumour environment. This webinar will explore the reasons that underlie this and discuss the innovative strategies and gene editing technologies that are being employed to overcome these limitations.
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Direct control of CAR T cells through small molecule-regulated antibodies

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By Kevin Lindquist, Christopher Kimberlin, Barbra Johnson Sasu, Javier Chaparro-Riggers
| Nature Verified
Abstract Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR) T cells. Many next generation antibody therapeutics achieve enhanced potency but often increase the risk of adverse events.
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