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HLA binding‐groove motifs are associated with myocarditis induction after Pfizer‐BioNTech BNT162b2 vaccination
1 INTRODUCTION Myocarditis is an inflammation of the heart muscle that may be caused by infectious and noninfectious factors.1 The inflammation may lead to more severe diseases, such as inflammatory cardiomyopathy (ICM).2 Excessive or persistent activation of the innate immune system has been previously shown to lead to an exaggerated and/or chronic inflammatory process that triggers myocardial destruction and remodelling, culminating in cardiac dysfunction.3 The severe acute respiratory...
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