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Practical Recommendations for Anticoagulation in Patients With Atrial Fibrillation
1 Introduction With a lifetime risk exceeding 1 in 4 persons [1, 2], atrial fibrillation (AF) is the most common cardiac arrhythmia and a major cause of morbidity, hospitalization and death. AF is associated with a twofold increase in mortality [3] and a fivefold increase in stroke risk [4]. Among AF patients, the lifetime risk of stroke without anticoagulation is approximately 1 in 3 [2, 5] and AF is estimated to be responsible for 15%–25% of all strokes [4, 6-8].
Association between the intensity of statin therapy and physical activity 1 year after acute coronary syndrome: a multicentre prospective cohort study in Switzerland
Methods The Special Program University Medicine-Acute Coronary Syndromes (SPUM-ACS) study is an observational prospective Swiss cohort of patients hospitalised for ACS in four university hospitals in Switzerland (Bern, Geneva, Lausanne and Zürich). Details concerning the SPUM-ACS study have been reported previously.11 The recruitment was performed from 2009 to 2017. Patients were eligible if they were 18 years and older, both men and women, presenting with the main diagnosis of ACS.
Routine beta‐blocker therapy after acute coronary syndromes: The end of an era?
1 INTRODUCTION Beta-blocker therapy has been shown to improve early and long-term cardiovascular outcomes following acute coronary syndromes (ACS).1, 2 However, most landmark trials were conducted in the 1980s and predate the advent of mechanical reperfusion therapy and modern pharmacologic secondary prevention, including intensive lipid-lowering therapy, antiplatelet agents and renin–angiotensin–aldosterone system inhibitors.1, 3 While the benefit of beta-blockers in patients with left...
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