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Barnaby W. Balmforth on Muck Rack

Barnaby W. Balmforth

As seen in: Nature
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Enrichment of mutated DNA enables ultra-sensitive ctDNA detection in NSCLC using shallow targeted sequencing

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By Hugh Russell, Daniel B Stetson, Katarzyna A. Anton, Maria Litovchenko, Ernesto Lowy-Gallego, Amy Lovell, James Hadfield, Paul Labrousse, Paulina K. Powalowska-Pickton, Sophie Hackinger, Magdalena Stolarek-Januszkiewicz, Barnaby W. Balmforth
| Nature Verified
Abstract Liquid biopsy assays using next-generation sequencing have emerged as a promising tool in cancer diagnostics to aid detection of minimal residual disease (MRD) and treatment monitoring. A key concern is the trade-off between sensitivity and sequencing depth, with ultra-sensitive techniques suffering from high costs.
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