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Evaluating miRNA Sequencing and Integrative Proteomics for Identifying Plasma miRNAs as Potential Pharmacodynamic Biomarkers of IFNβ‐1a Biologics
1 Introduction Omics technologies offer great potential for biomarker discovery in drug development, enabling the measurement of genome, transcriptome, proteome, and metabolome features [1-3]. Blood plasma contains miRNAs, which are small non-coding RNAs of approximately 21–23 nucleotides (nts), involved in the regulation of several physiological processes [4].
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