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Barry Li

As seen in: Nature, BioRxiv, Gastrointestinal Endoscopy
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Articles

Environment-Induced Exciton Renormalization in the Photosystem II Reaction Center Click to copy article link Article link copied!

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By Tucker Allen, Barry Li, Nadine C. Bradbury
| dx.doi.org
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Su1053 A RARE CASE: HUMAN INTESTINAL SPIROCHETOSIS AS A CAUSE OF CHRONIC DIARRHEA IN AN IMMUNOCOMPETENT PATIENT

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By Daniel Najar, Barry Li, Hannah Wang
| Gastrointestinal Endoscopy Verified
Also available on ScienceDirect
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Bioenergetic stress potentiates antimicrobial resistance and persistence - Nature Communications

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By Barry Li, Madison Garcia, Ting-Yu Chu, Xiaoyang Su
| Nature Verified
Abstract The bactericidal action of some antibiotics is associated with increased ATP consumption, cellular respiration, and reactive oxygen species (ROS) formation. Here, we investigate the effects of ‘bioenergetic stress’, induced by constitutive hydrolysis of ATP and NADH, on antibiotic efficacy in Escherichia coli. We show that bioenergetic stress potentiates the evolution of antibiotic resistance via enhanced ROS production, mutagenic break repair, and transcription-coupled repair.
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