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Barry Reid

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Bioinspired 3D microprinted cell scaffolds: Integration of graph theory to recapitulate complex network wiring in lymph nodes

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By Barry Reid, Veronika Lachina, Sophie E Acton
| Wiley Online Library Verified
1 INTRODUCTION 3D cell scaffolds used in tissue engineering and disease modelling are typically modelled after structurally complex fibrous or porous networks in natural tissue microenvironments, such as the extracellular matrix (ECM).[1-3] Lately, modelling efforts have broadened to encompass the lymph node, a crucial organ of which there are hundreds dispersed across the lymphatic system. Lymph nodes act as information-exchange hubs for immune cells.
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