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Barry Rosen

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Articles

Chemogenomic maps reveal a PRDX1-dependent iron–damage axis in the DNA damage response

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By Thomas O’Loughlin, Abolfazl Arab, Ashir A. Borah, Valentina Quarantotti, Kevin Lou, Barry Rosen, Jacob Corn, Davide Gianni, Josep V. Forment, Luke A Gilbert, Sara Misiukiewicz, Elizabeth Montesano, Christopher Yogodzinski, Shaheen Kabir
| Nature Verified
Abstract The DNA damage response (DDR) is a sophisticated network of cellular pathways whose perturbation leads to genome instability and is a key hallmark of oncogenesis. Here, we present data from 32 genome-scale loss-of-function CRISPR interference chemical–genetic screens with inhibitors targeting core constituents of the DDR machinery (PARP, ATR, ATM, DNAPK and WEE1), as both single agents and in combination with poly(ADP-ribose) polymerase inhibitors.
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Barry S. Rosen | Authors | CancerNetwork

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By Barry Rosen
| ONCOLOGY journal Verified
Articles by Barry S. Rosen In a retrospective multi-institution study of 267 early-stage breast cancer patients, the TumorSight Viz AI algorithm achieved landmark identification and measurement accuracy comparable to inter-radiologist variability, generating results in an average of 8 minutes per patient.
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FTC’s noncompete ban is dead, but its efforts to limit noncompetes survives

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By Barry Rosen, Charles R. Bacharach
| The Daily Record (Baltimore, MD) Verified
In 2024, the Federal Trade Commission promulgated a nationwide rule banning most non-competition agreements. After more than a year of litigation holding up enforcement of the FTC’s rule, the Trump administration, on September 5, 2025, announced that it would dismiss its attempts to overturn the injunctions that ban the enforcement of the rule.
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