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Bart A. A

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CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology - Acta Neuropathologica Communications

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By Institut Blood, Caen Cedex, “Momentum” Laboratory, Bart A. A
| Biomed Central (BMC)
Formation of IAs was induced by local microinjection of elastase (1µL, 35 IU) behind the MCA bifurcation (Fig. 1a; Additional file 1: Figure 1a) and immediately followed by subcutaneous Angiotensin II (Ang II) osmotic pump (800 µg in 90 µL of saline solution; diffusion rate 37 ng/min/14 days) insertion (Fig. 1a; Additional file 1: Figure 1a). This model is a variation of the model previously described by Nuki et al. [37], inspired by models developed for abdominal aortic aneurysm studies [2].
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