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Bart A Pannebakker on Muck Rack

Bart A Pannebakker

As seen in: BioRxiv
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Articles

Investigating multiple types of resistance against a homing gene drive in European populations of Drosophila melanogaster

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By Nicky R. Faber, Jackson Champer, Bart A Pannebakker, Bas J Zwaan
| BioRxiv
Abstract Gene drive technology may be a valuable tool for addressing several contemporary challenges, including combating disease vectors, conserving biodiversity, and controlling agricultural pests. Homing gene drives spread through a population by copying themselves onto the homologous chromosome in the germline of heterozygous individuals.
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Uncovering large effect loci and epistasis for lifespan in standing genetic variation in the fruit fly Drosophila melanogaster

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By Klaas Vrieling, Jan E. Kammenga, Jelle Zandveld, Bart A Pannebakker
| BioRxiv
Abstract Lifespan is a heritable trait with a polygenic architecture. Experimental evolution in combination with re-sequencing has often been used to identify candidate loci for lifespan in Drosophila melanogaster. Previous experiments showed that Drosophila populations experimentally evolved to increase late-life reproduction showed a correlated responses in development time, body size, but also lifespan.
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