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Bart AA Franx

As seen in: SAGE Publishing
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Articles

Chronic hypertension and perfusion deficits conjointly affect disease outcome after tPA treatment in a rodent model of thromboembolic stroke

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By Bart AA Franx, Rick M. Dijkhuizen, Ivo ACW Tiebosch
| SAGE Publishing
Get full access to this article View all access and purchase options for this article. References 1. El Amki M, Wegener S. Improving cerebral blood flow after arterial recanalization: a novel therapeutic strategy in stroke. Int J Mol Sci 2017; 18: 2669. 2. van der Knaap N, Franx BAA, Majoie CBLM, et al. Implications of post-recanalization perfusion deficit after acute ischemic stroke: a scoping review of clinical and preclinical imaging studies. Transl Stroke Res 2024; 15: 179–194. 3.
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Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats - Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements - Bart AA Franx, Florent Lebrun, Lois Chin Joe Kie, Thomas

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By Thomas Deffieux, Denis Vivien, Bart AA Franx, Florent Lebrun
| SAGE Publishing
Introduction Perfusion imaging techniques are instrumental in clinical acute ischemic stroke (AIS) diagnosis, patient selection in clinical trials,1,2 and translational stroke research. Tomographic perfusion imaging allows in vivo spatial measurement of hemodynamic indices during ischemia and after reperfusion. Hemodynamic parameters, such as cerebral blood flow (CBF) and volume (CBV), can differentially and complementarily report tissue perfusion and may predict subsequent tissue outcome.
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