Bart Boerrigter

Background Several hereditary disorders, with highly variable and sometimes difficult to recognize manifestations, can present with a spontaneous pneumothorax. Options to perform DNA-testing have changed rapidly, as a result of which physicians of diverse disciplines are coming into contact with hereditary disorders. Case description Two patients with a history of multiple spontaneous pneumothoraxes were seen at the outpatient clinic of the department of Clinical Genetics.

Discussion In this trial, we showed that using ULDCT in the diagnostic work-up of patients suspected of non-traumatic pulmonary disease at the ED resulted in functional health outcomes at 28 days that are at least similar to those obtained with management guided by CXR, with minimal differences in ED length of stay, hospital admissions, hospital length of stay and mortality rates, less additional imaging but more incidental findings.