Bart Claushuis
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Elucidation of the Glycan Structure of the b-type Flagellin of Pseudomonas aeruginosa PAO1
Bacterial flagella are intricate, whip-like appendages that extend from the cell bodies of many motile bacteria, playing a crucial role in their locomotion and environmental navigation. (1) These structures are not only essential for bacterial motility but also contribute significantly to pathogenicity, colonization, and biofilm formation.
Characterization of the Clostridioides difficile 630Δerm putative Pro-Pro endopeptidase CD1597
Article metrics loading... /content/journal/acmi/10.1099/acmi.0.000855.v3 Download as PowerPoint /deliver/fulltext/acmi/6/10/acmi000855.v3.html?itemId=/content/journal/acmi/10.1099/acmi.0.000855.v3&mimeType=html&fmt=ahah References Perez-Riverol Y, Bai J, Bandla C, García-Seisdedos D, Hewapathirana S et al. The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences. Nucleic Acids Res 2022; 50:D543–D552 [View Article] [PubMed] [Google Scholar] Dubberke E.
Proteolytic activity of surface‐exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile
1 INTRODUCTION When entering a host, pathogenic bacteria are exposed to a plethora of stress-inducing conditions. These may include low pH, lysozyme, antimicrobial peptides, osmotic stress, elevated temperatures, the complement system, exposure to immune cells and their products such as antibodies, and many others. These conditions often result in unfolding of proteins in the bacterial envelope, which induces membrane stress and can eventually lead to cell death (Jordan et al., 2008).
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