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Bart Geverts

As seen in: Wiley Online Library, BioRxiv
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Articles

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

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By Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti
| Wiley Online Library Verified
AI artificial intelligence AR androgen receptor EGFP enhanced green fluorescent protein FRAP fluorescent recovery after photobleaching gRNA guide RNA OH-F hydroxyflutamide pFRAP parallel fluorescent recovery after photobleaching RCM ReScan confocal microscope ROI region of interest sFRAP sequential fluorescent recovery after photobleaching SMC1A structural maintenance of chromosomes protein 1A SMC3 structural maintenance of chromosomes protein 3 STAG1 stromal antigen 1 STAG2 stromal antigen 2...
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Regulation of XPG-DNA damage binding dynamics by pre- and post-incision nucleotide excision repair factors and EXO1

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By Cristina Ribeiro-Silva, Carlota Davó-Martínez, Alba Muniesa-Vargas, Bart Geverts
| BioRxiv
Abstract The XPG endonuclease plays a crucial role in nucleotide excision repair (NER) and other genome maintenance pathways. Precise regulation of XPG recruitment and activity during DNA repair is essential to avoid erroneous DNA incisions and genomic instability. In this study, we employed live-cell imaging to investigate how XPG function is regulated during NER, focusing on its dynamic interactions with key factors involved in the pre- and post-incision steps.
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