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Bart Jacobs

As seen in: Color Research & Application, Nature, Wiley Online Library, arXiv, MDPI, Taylor & Francis Online, ZDNet, ACM - Association for Computing Machinery, JAMA (The Journal of the American Medical Association), JAMA Oncology and
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Articles

Distinct gut microbial signatures associated with disease onset and clinical course in Guillain–Barre syndrome

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By Israt Jahan, Asaduzzaman Asad, Ruma Begum, Mohammad Jubair, Quazi Deen Mohammad, Sonja E. Leonhard, Bart Jacobs, Hubert P Endtz, Zhahirul Islam
| Nature Verified
Abstract The Gut microbiota is crucial for regulating immune responses in autoimmune neuropathies like Guillain–Barré syndrome (GBS). Yet, its influence on disease course and recovery remains unclear. This study examined gut microbiota dysbiosis in 57 GBS patients and 57 age- and gender-matched healthy controls, following 32 patients for six months to identify microbial signatures associated with disease onset and clinical progression.
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A pilot study on midazolam sedation for murine echocardiography: A potential alternative to isoflurane anesthesia and awake imaging

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By Bart Jacobs, Lies Langouche, Jan D'hooge, Sarah Derde
| Wiley Online Library Verified
1 INTRODUCTION Echocardiography is a widely used, non-invasive tool to assess cardiac function in mouse models of cardiovascular disease (Riehle & Bauersachs, 2019). Current guidelines published recommend the use of anesthesia as the primary approach for echocardiographic imaging in mice (Lindsey et al., 2018). Anesthesia facilitates standardization and reduces variability caused by movement and sympathetic activation.
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When children diagnosed with Guillain-Barré syndrome do not recover

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By Bart Jacobs
| The Lancet Verified
CommentVolume 24, Issue 8p629-630 aDepartment of Pediatric Neurology, Erasmus MC Center of Expertise for Neuromuscular Diseases, University Medical Center, Rotterdam, Netherlands bDepartments of Neurology and Immunology, Erasmus MC Center of Expertise for Neuromuscular Diseases, University Medical Center, Rotterdam, 3000 CA, Netherlands Publication History: Published August 2025 DOI: 10.1016/S1474-4422(25)00240-6 External LinkAlso available on ScienceDirect External Link Copyright: © 2025...
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