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Bart Naughton

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Articles

Applications of single-cell RNA sequencing in drug discovery and development - Nature Reviews Drug Discovery

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By Joon Lee, Euphemia Mutasa-Gottgens, Bart Naughton, Wendi A. Bacon, Yong Huei Wang, Melissa Mendez, Jon Hill, Namit Kumar, Xiaohong Cao, Ji Wen, Andrew Leach
| Nature Verified
Abstract Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods, together with associated computational tools and the growing availability of public data resources, are transforming drug discovery and development. New opportunities are emerging in target identification owing to improved disease understanding through cell subtyping, and highly multiplexed functional genomics screens incorporating scRNA-seq are enhancing target credentialling and prioritization.
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