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Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study

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By Gijs H. Goossens, Shauna D. O’Donovan, Miranda T. Schram, Bart van Sloun
| paperity.org
PLOS ONE, Jul 2023 Computational models of human glucose homeostasis can provide insight into the physiological processes underlying the observed inter-individual variability in glucose regulation. Modelling approaches ranging from “bottom-up” mechanistic models to “top-down” data-driven techniques have been applied to untangle the complex interactions underlying progressive disturbances in glucose homeostasis.
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