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Bartika Ghoshal on Muck Rack

Bartika Ghoshal

As seen in: ACS Publications, BioRxiv
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Articles

Neutrophil-Derived Extracellular Vesicles for Facile Delivery of Diagnostic Agents to Tumor Microenvironments

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By Bartika Ghoshal, Preeti Bhatt, Subinoy Rana, Pooja Annasaheb Patkulkar
| ACS Publications
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Ex Vivo Delivery of mRNA to Immune Cells Via a Non-Endosomal Route Obviates the Need for Nucleoside Modification

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By Debajyoti Chakraborty, Manish Nag, Raghavan Varadarajan, Bartika Ghoshal
| BioRxiv
Abstract Base modification and the use of lipid nanoparticles (LNPs) are thought to be essential for efficient in vivo delivery and expression of mRNA. However, for ex vivo immune cell engineering, the need for either of the two is unclear. Previous reports have suggested that nucleic acids may be efficiently delivered to immune cells ex vivo, through a non-endosomal delivery route, but the need for base modification has not been determined.
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